Carboxylic acids and derivatives
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 2mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
Apexbio Technology LLC CL 316243 disodium salt 151126-84-0 10mg
CL 316243 disodium salt is a small-molecule agonist targeting the 3-adrenergic receptor It is designed to activate 3 receptors thereby modulating lipolytic and thermogenic pathways predominantly in adipose tissues CL 316243 disodium salt exerts its biological activity by selectively binding to 3-adrenergic receptors leading to enhanced adipocyte-mediated lipid metabolism In experimental rodent models administration of CL 316243 increases insulin sensitivity and reduces obesity-related hyperglycemia by promoting glucose uptake primarily in adipose tissue Based on these pharmacological properties CL 316243 disodium salt holds research potential in the study of 3 receptor-mediated metabolic mechanisms and the exploration of therapeutic strategies for metabolic disorders such as obesity and type 2 diabetes
Alkali Scientific Nalidixic Acid Sodium Salt, 500 Grams
Nalidixic Acid Sodium Salt, 500g, is a laboratory-grade antibiotic used primarily in microbiological research and antimicrobial testing. Nalidixic acid belongs to the quinolone class of antibiotics, which work by inhibiting bacterial DNA gyrase, leading to impaired DNA replication and cell death. The 500g quantity is designed for large-scale testing and studies, including high-throughput antimicrobial susceptibility testing and research into bacterial resistance mechanisms. It is particularly useful in the study of Gram-negative bacterial infections and is widely used in clinical microbiology laboratories for evaluating the effectiveness of quinolone drugs in treating urinary and gastrointestinal infections.
Apexbio Technology LLC Concanavalin A (Con A)-HyperFluor 594 5x5mg(5 mg/mL)
Concanavalin A (Con A) derived from Canavalia ensiformis (jack bean) is a plant lectin protein with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 ion and one Mn2 ion and has one carbohydrate binding site Con A is capable of binding to various glycoproteins glycolipids and -D-glucose and -D-mannose residues HyperFluor 594 is a fluorescent dye that emits green fluorescence under UV light (Ex/Em 590 nm/617 nm) This conjugation significantly enhances the visualization capability of Con A-HyperFluor 594 for detecting carbohydrate molecules on the cell surface This product is a solution-form Concanavalin A labeled with HyperFluor 594 It is applicable in glycobiology research serving as a probe to detect carbohydrate molecules on the cell surface and analyzed effectively using flow cytometry Applying IHC staining procedures with this product allows visualization of carbohydrate distribution in tissues or cells under a fluorescence microscope
eMolecules 149-11-1 | Ambeed | Copper(II) 2-ethylhexanoate | 1g | 588343068 | A652646 | MFCD00015695 | 349.958 | C16H30CuO4
Ambeed | 2-Isopropylthiazole-5-carbaldehyde | 100mg | 600827271 | A108624 | 207675-84-1 | MFCD14615182 | 155.220 | C7H9NOS
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ILEX LIFE SCIENCES LLC ALSEVERS SOLUTION 500 ML
PAN-Biotech Alsever's Solution (500 ml). Ca/Mg: Without calcium and magnesium. BICARBONATE: Without sodium bicarbonate. PHENOL RED: Without Phenol Red. STERILE: Yes. STORAGE: +2-8°C. PRODUCT CATEGORY: Balanced salt solutions. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. DESCRIPTION: PAN-Biotech Alsever's Solution is an isotonic balanced solution. It is used as an anticoagulant or blood preservative. Alsever's Solution enables whole blood to be stored at refrigerator temperature up to 10 weeks.
Selleck Chemical LLC Nigericin sodium salt
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that works by acting as an H K and Pb2 ionophore Nigericin can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes
Apexbio Technology LLC Cefotaxime (sodium salt)(Synonyms: Claforan, Cefotaxime Sodium, Cefotaxim sodium salt, Cefotaxime Na, Sodium cefotaxime), 10mM (in 1mL DMSO), CAS: 64485-93-4.
Cefotaxime sodium (CAS 64485-93-4) is a third-generation cephalosporin antibiotic belonging to the -lactam group characterized by inhibition of bacterial cell-wall synthesis through binding to penicillin-binding proteins In vitro analyses show strong inhibitory efficacy against various bacterial species notably cefotaxime exhibits an MIC below 0 1 g/ml against Streptococcus pneumoniae It also demonstrates high activity against Haemophilus influenzae including -lactamase-producing strains In vivo mouse model studies revealed that combination therapy of cefotaxime with minocycline enhanced survival following Vibrio vulnificus infection compared to single-agent treatments Clinically cefotaxime has been evaluated in pneumonia therapy demonstrating good tolerance and therapeutic utility in targeting susceptible bacterial pathogens
Apexbio Technology LLC SIVELESTAT-SODIUM-SALT-50MG
Sivelestat sodium salt (CAS No 150374-95-1) is a serine protease inhibitor primarily used in biomedical research investigating inflammation and sepsis Originating from pharmacological studies aimed at treating acute lung injury it works by inhibiting neutrophil elastase a key enzyme in inflammatory pathways This inhibition helps reduce tissue damage and inflammatory responses In vitro Sivelestat sodium salt exhibits activity in the nanomolar to low micromolar range effectively attenuating enzyme activity It is commonly applied in cell models to investigate inflammatory processes and in animal studies focusing on respiratory diseases Moreover it is utilized in drug screening to evaluate the potential efficacy of new anti-inflammatory compounds Experimental concentrations typically depend on the specific research design ensuring the flexibility needed to align with diverse experimental parameters
Apexbio Technology LLC CEFSULODIN-SODIUM-SALT-500MG
Cefsulodin (sodium salt) (CAS No 52152-93-9) is a -lactam antibiotic primarily used in microbiological research Originating from the cephalosporin family it functions by inhibiting bacterial cell wall synthesis targeting penicillin-binding proteins particularly effective against Pseudomonas aeruginosa Its in vitro activity is observed within the nanomolar to low micromolar range making it a valuable tool in evaluating bacterial susceptibility Cefsulodin s applications extend to various experimental setups including cell culture models animal studies and drug screening assays for antibacterial agents It serves as a benchmark in establishing the efficacy of new antimicrobial compounds Experimental concentrations typically depend on the specific research design allowing flexibility in its application to suit diverse investigative needs
![Alkali Scientific X GlcA Sodium Salt [5 Bromo 4 chloro 3 indolyl β D glucuronic acid, sodium salt trihydrate], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660319.jpg-250.jpg)
Alkali Scientific X GlcA Sodium Salt [5 Bromo 4 chloro 3 indolyl β D glucuronic acid, sodium salt trihydrate], 100 Mg
X GlcA Sodium Salt [5 Bromo 4 Chloro 3 indolyl β-D-glucuronic acid, sodium salt trihydrate], 100 mg is a chromogenic substrate used for detecting β-glucuronidase activity in biochemical assays. Upon hydrolysis by the enzyme, the substrate produces a blue color, making it ideal for enzyme activity detection in microbiological and biochemical studies. It is particularly useful for identifying microorganisms capable of hydrolyzing glucuronic acid. X GlcA Sodium Salt is widely used in genetic studies, enzyme characterization, and microbial screening, providing a reliable method for detecting β-glucuronidase in recombinant microorganisms or natural microbial populations.